Walk into any pharmacy and you’ll find aisle after aisle of supplements promising more energy, stronger immunity, sharper focus, and longer life. With so many options, it’s no surprise that many people feel overwhelmed or unsure where to begin.
At Griffin Concierge Medical, we take a different approach. Supplementation can play a meaningful role in optimizing health and supporting longevity, but only when it’s used intentionally and guided by data. Our model of concierge medicine at Griffin is designed to make this process clear, personalized, and clinically appropriate.
For convenience, we offer a curated selection of high-quality, physician-vetted supplements available through our office (with in-office pickup or home delivery options). We also partner with Fullscript so members can access discounted, professional-grade supplements through our Griffin store to help keep your supplement plan aligned with your broader longevity and prevention strategy.
Supplements Are Not One-Size-Fits-All
Two people can take the same supplement and experience very different outcomes. Without understanding your baseline nutrient status, medications, health history, genetics, and lifestyle factors, supplementation becomes guesswork. That’s why at Griffin, we begin with data and build from there.
Step One: Comprehensive Lab Testing
Before recommending supplements, your Griffin physician typically orders personalized lab testing to identify deficiencies, imbalances, and trends that influence how your body uses nutrients. Depending on your health goals and clinical history, testing may include several key categories.
Micronutrient and Vitamin Status
Lab testing helps identify deficiencies or suboptimal levels of essential nutrients. Common areas we evaluate may include:
- Vitamin D
- B vitamins (including B12)
- Iron and ferritin
- Magnesium
Two of the most common patterns we see are low vitamin D status and low or borderline vitamin B12 status.
Vitamin D deficiency is widespread due to limited sun exposure, age-related changes in vitamin D synthesis, and insufficient intake from food alone. Low levels may affect bone health, immune function, muscle strength, and inflammatory disease. (https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/)
Vitamin B12 deficiency or insufficiency is also common, particularly with increasing age, absorption challenges, certain medications, and dietary patterns that limit B12-rich foods. Low or borderline levels can contribute to fatigue, cognitive changes, mood symptoms, and neurologic effects, often misattributed to stress or “just getting older.” (https://ods.od.nih.gov/factsheets/Vitaminb12-HealthProfessional/)
Based on your individual goals, history, and risk factors, your Griffin physician may recommend expanded testing beyond standard panels. If you’re interested in deeper micronutrient testing, talk to your Griffin physician.
Inflammatory Markers
Chronic inflammation can increase nutrient needs and affect how the body metabolizes and utilizes supplements. Testing helps identify patterns that may contribute to fatigue, pain, metabolic dysfunction, or accelerated aging, so your plan can target root causes rather than stacking random products.
Metabolic and Cardiovascular Markers
Markers related to blood sugar regulation, insulin resistance, lipid patterns, and cardiovascular risk can influence supplement selection. In certain situations, for example, omega-3 fatty acids may be prioritized for cardiometabolic support based on your personal risk profile and lab findings.
Hormonal and Stress-Related Markers
Hormonal balance and chronic stress shape nutrient utilization, recovery capacity, and resilience. Testing can reveal hormonal patterns that may benefit from targeted support and highlight nutrient depletion associated with prolonged stress.
Digestive Function and Nutrient Absorption
Even with an excellent diet, poor digestion or absorption can lead to deficiencies. When indicated, testing can reveal markers of malabsorption or gut-related contributors to nutrient depletion so we can choose forms and dosing strategies that actually work for your physiology.
Step Two: Understanding Genetic Influences
Lab testing shows your current nutrient status. Genetic testing can help explain how your body processes nutrients over time to offer deeper context for why certain deficiencies recur or why some people require a different strategy to maintain optimal levels.
Our members have access to advanced whole-genome analysis through New Amsterdam Genomics (NAG). Your genomic data is reviewed by your Griffin physician in collaboration with a NAG geneticist, and your dataset can be updated over time as new scientific discoveries emerge.
How genetics can inform supplementation
Genomic insights may help your physician better understand:
- How efficiently certain vitamins are absorbed or utilized
- Variations in pathways related to methylation and detoxification
- Tendencies related to inflammation, oxidative stress, and metabolism
Genetic variants don’t determine outcomes, but they can influence what your body is likely to need and how aggressively deficiencies should be corrected. For more information about genomic testing, reach out to your Griffin physician or patient care coordinator.
Step Three: Building Your Personalized Supplement Plan
After reviewing your lab results, health history, and goals (and genetics when applicable), your Griffin physician can build an individualized supplement plan. Our focus is simple: every supplement should serve a purpose, fit your physiology, and be monitored over time.
Curated, high-quality supplements available in-house
For your convenience, we stock a selection of vetted supplements from trusted manufacturers that are commonly indicated, well-tolerated, and clinically useful for many members. These supplements are often used to support:
- Vitamin and mineral repletion
- Cardiovascular and inflammatory health
- Gut and immune function
- Sleep and mood support
- Hormonal balance
- Mitochondrial health
- Liver support
As an added benefit, Griffin members receive complimentary B12 injections at our office. Ask your patient care coordinator to schedule your appointment, or stop in when it’s convenient.
Discounted, professional-grade supplements through Fullscript
Through our Fullscript partnership, members can order professional-grade supplements online in a streamlined way that supports continuity of care. Your Griffin physician can create a personalized favorites list to reduce overwhelm and keep selections aligned with your broader plan. If you’d like to get started with Fullscript, ask your Griffin physician to send you an invitation.
Recommended supplements through other sources
At times, your Griffin physician may share links to supplements available through other trusted sources if that best fits your needs. The goal is always the same: the right supplements for the right reasons at the right time.
Step Four: Monitoring Progress and Adjusting
Supplementation is not a “set it and forget it” process. As your body adapts, lab values change, and goals evolve, your supplement plan should evolve as well.
We recheck relevant labs at appropriate intervals to confirm that supplements are doing what they were intended to do. Lab values are only part of the picture, so your physician will also track real-world outcomes such as:
- Energy and stamina
- Cognitive clarity and focus
- Sleep quality
- Mood and stress resilience
- Digestive comfort
- Overall wellbeing
Short-Term Correction vs. Long-Term Longevity
Sometimes supplementation is corrective and short-term: replenishing deficiencies, supporting recovery, or addressing temporary imbalances. Longevity-focused supplementation is different. It’s about supporting the biological systems that influence how we age to complement your full preventive plan.
When used appropriately, supplements may support:
- Mitochondrial function and cellular energy
- Inflammatory balance and cardiometabolic risk
- Hormonal balance and detoxification pathways
- Sleep quality, recovery, and stress resilience
- Maintaining optimal nutrient status with aging
Building a Strong Foundation for Supplement Use
Supplements work best when they support healthy lifestyle habits. A diet rich in whole foods provides the vitamins, minerals, fiber, and nutrients that supplements are designed to complement, not replace. Regular physical activity, restorative sleep, and daily stress management also influence how effectively your body uses nutrients.
If you want supplements to “work,” the fundamentals still matter. We often reinforce these foundations alongside supplementation:
- Protein-forward, whole-food nutrition
- Strength training and consistent movement
- Sleep consistency and sleep quality support
- Stress management strategies that are sustainable
Conclusion
At Griffin Concierge Medical, we help patients use supplements as an evidence-informed tool for optimizing health. Supplements work best when layered into your overall prevention and longevity strategy and guided by a high-touch, concierge-style care model that includes testing, personalization, and ongoing monitoring.
If you’d like to get started on your supplementation plan, contact your Griffin physician or patient care coordinator!
Works Cited
- “Vitamin D – Health Professional Fact Sheet.” Office of Dietary Supplements, National Institutes of Health, https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/. Accessed 29 Dec. 2025.
- “Vitamin B12 – Health Professional Fact Sheet.” Office of Dietary Supplements, National Institutes of Health, https://ods.od.nih.gov/factsheets/Vitaminb12-HealthProfessional/. Accessed 29 Dec. 2025.
- “Vitamin D.” The Nutrition Source, Harvard T.H. Chan School of Public Health, https://nutritionsource.hsph.harvard.edu/vitamin-d/. Accessed 29 Dec. 2025.
- “Fullscript: Easily Build Supplement Plans for Optimal Health.” Fullscript, https://fullscript.com/. Accessed 29 Dec. 2025.
